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Hofmann Elimination



Hofmann Elimination
  • Is the spontaneous inactivation of the drug in the body without the involvement of any enzyme.

Example
  • Atracurium

  • Cisatracurium

Advantage

Elimination of such drugs is not affected in hepatic and renal insufficiency

can be safely used in such patients.

 

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Pharmacodynamics > ▶️ Agonist, Partial Agonist, Antagonist and Inverse Agonist: Difference Explained
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